Prebiotic UG1601 mitigates constipation-related events in association with gut microbiota: A randomized placebo-controlled intervention study

Table 2 Stool frequency score of 40 mildly constipated subjects treated with either placebo or prebiotics at baseline and 4 wk of intervention

Time point	Placebo (n = 20)	Prebiotics (n = 20)	P value1
Baseline	2.47 ± 0.22	2.35 ± 0.18	0.667
Week 4	4.11 ± 0.21	4.10 ± 0.25	0.174
P value2	0.002	< 0.001
Change of score	1.55 ± 0.33	1.75 ± 0.22	0.620

¹Calculated using the Student’s t-test (between groups).

²Calculated using paired t-test (within a group). Data are expressed as the mean ± standard error of the mean. Change in score was calculated by subtracting the values at week 4 from those at baseline.