Apparent diffusion coefficient-based histogram analysis differentiates histological subtypes of periampullary adenocarcinoma

Table 4 Diagnostic performance of the volumetric histogram parameters at b₁₀₀₀

ADC parameter	AUC (95%CI)	Cut-off (10-3 mm2/s)	Sensitivity (%)	Specificity (%)
Mean	0.762(0.601-0.882)	1.40	91	52
5th	0.703 (0.538-0.837)	1.09	78	58
10th	0.723 (0.558-0.825)	0.90	57	82
25th	0.742 (0.579-0.867)	1.34	83	59
50th	0.781 (0.623 0.896)	1.50	91	59
75th	0.774 (0.613-0.892)	1.44	78	69
90th	0.750 (0.581-0.877)	1.52	82	67
ADCmax	0.747(0.585-0.871)	1.63	70	82

ADC: Apparent diffusion coefficient; AUC: Area under the curve; CI: Confidence interval.