Interplay between post-translational cyclooxygenase-2 modifications and the metabolic and proteomic profile in a colorectal cancer cohort

Figure 3 High resolution magic angle spinning analysis of tumor tissue. A: Schematic diagram of high resolution magic angle spinning spectra of tumor tissue (red line) and non-tumor tissue (blue line). Black arrows indicate two peaks corresponding to taurine δ ppm 3.26 and 3.42. B: Graph represents the quantification of both taurines normalized by creatine of tumor (T) and non-tumor (N) tissue. C and D: Correlation graphs of taurine 3.26 (C) and taurine 3.42 (D) in T vs N subdivided depending on the stage of the Tumor: 1-2 vs 3-4. E and F: Graphs represent the quantification of phosphocholine (E) or lactate (F) in T vs N. n = 29. Graphs show mean ± SD. ^bP ≤ 0.01, ^cP ≤ 0.001 of T vs N and ^dP ≤ 0.05, ^fP ≤ 0.001 between stages in tumors. T: Tumor; N: Non-tumor.