Differentially expressed long noncoding RNAs and regulatory mechanism of LINC02407 in human gastric adenocarcinoma

Figure 7 LINC02407 influences gastric cancer through the LINC02407-miR-6845-5p and miR-4455-adhesion G protein-coupled receptor D1 pathways. A: Sankey diagram for the competing endogenous RNA network in LINC02407. This Sankey plot shows the quantity of evidence for LINC02407 on the left-hand side, miR-6845-5p and miR-4455 in the middle, and the quantity of evidence for potential target mRNAs on the right-hand side of the plot. Each rectangle represents a gene, and the size of the rectangle represents the degree of connection of each gene; B: Western blot assay of adhesion G protein-coupled receptor D1, cholinergic receptor nicotinic delta, IGLON5, KRI1, and troponin I1 proteins differentially expressed in HGC-27 cells under different treatments. Data are reported as the mean ± SD. ^aP < 0.05, ^bP < 0.01, and ^eP < 0.001 for between-group comparisons. NC: Negative control; ADGRD1: Adhesion G protein-coupled receptor D1; CHRND: Cholinergic receptor nicotinic delta; IGLON5: IgLON family member 5; TNNI1: Troponin I1; LncRNA: Long noncoding RNA; miRNA: MicroRNA.