Differentially expressed long noncoding RNAs and regulatory mechanism of LINC02407 in human gastric adenocarcinoma

Figure 6 Hsa-miR-6845-5p and hsa-miR-4455 have negative effects on gastric cancer. A: Luciferase reporter assay verifying hsa-miR-6845-5p and hsa-miR-4455 as direct targets of hsa-miR-6845-5p and hsa-miR-4455; B: Determination of the effects of hsa-miR-6845-5p-mimic and hsa-miR-4455-mimic on cell viability in HGC-27 cells; C: Evaluation of the influence of hsa-miR-6845-5p-mimic and hsa-miR-4455-mimic on HGC-27 cell apoptosis; D: Evaluation of the effect of hsa-miR-6845-5p-mimic and hsa-miR-4455-mimic on invasion of HGC-27 cells. Data are reported as the mean ± SD. ^aP < 0.05, ^bP < 0.01, and ^eP < 0.001 for between-group comparisons. NC: Negative control.