STW 5 is effective against nonsteroidal anti-inflammatory drugs induced gastro-duodenal lesions in rats

Figure 2 Histopathological changes in rat stomach. A: Untreated controls showing a normal histological structure of gastric layers (mucosa, submucosa and musculosa); B: Diclofenac treated rats, showing multiple focal necrosis of gastric mucosa associated with mononuclear cell infiltration (black arrows), sub-mucosal edema and inflammatory cells infiltration (yellow arrow); C: Diclofenac together with omeprazole treated rats, showing sub-mucosal edema (black arrow) and congested sub-mucosal blood vessel (yellow arrow); D: Diclofenac together with STW 5 treated rats showing no histopathological alterations.