Allicin as add-on therapy for Helicobacter pylori infection: A systematic review and meta-analysis

doi:10.3748/wjg.v25.i39.6025

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World Journal of Gastroenterology

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1007-9327

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Meta-Analysis

World J Gastroenterol. Oct 21, 2019; 25(39): 6025-6040
Published online Oct 21, 2019. doi: 10.3748/wjg.v25.i39.6025

Table 6 Subgroup analyses of side effect rates

Comparison	Side effect rate (%)		Heterogeneity		OR	95%CI	P value
Comparison	Allicin group	Control	I² (%)	P value	OR	95%CI	P value
Allicin + PTT vs PTT[17-20] (ITT)	7.38	13.51	6.66	0.36	0.52	0.22-1.20	0.125
Allicin + PTT vs PTT[17-20] (PP)	5.92	9.57	0	0.59	0.61	0.32-1.16	0.132
Allicin-PPI-B-T-C vs PPI-B-T-C[21,22] (ITT/PP)	4.49	5.77	0	0.69	0.77	0.28-2.13	0.612
Allicin-PPI-Am-F vs PPI-Am-F[18,20] (ITT/PP)	2.27	7.95	0	0.85	0.27	0.054-1.34	0.110

PPI: Proton pump inhibitor; PTT: Proton pump inhibitor triple therapy; Am: Amoxicillin; F: Furazolidone; C: Clarithromycin; T: Tinidazole; B: Bismuth potassium citrate tablets; ITT: Intent-to-treat analysis; PP: Pre-protocol analysis; OR: Odds ratio; CI: Confidence interval.

Citation: Si XB, Zhang XM, Wang S, Lan Y, Zhang S, Huo LY. Allicin as add-on therapy for Helicobacter pylori infection: A systematic review and meta-analysis. World J Gastroenterol 2019; 25(39): 6025-6040
URL: https://www.wjgnet.com/1007-9327/full/v25/i39/6025.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i39.6025