Allicin as add-on therapy for Helicobacter pylori infection: A systematic review and meta-analysis

doi:10.3748/wjg.v25.i39.6025

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World Journal of Gastroenterology

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1007-9327

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Meta-Analysis

World J Gastroenterol. Oct 21, 2019; 25(39): 6025-6040
Published online Oct 21, 2019. doi: 10.3748/wjg.v25.i39.6025

Table 4 Subgroup analyses of healing rates of peptic ulcers

Comparison	Healing rate (%)		Heterogeneity		OR	95%CI	P value
Comparison	Allicin group	Control	I² (%)	P value	OR	95%CI	P value
Allicin + PTT vs PTT[15-18,20] (ITT)	80.32	68.29	0	0.527	2.14	1.39-3.29	0.001
Allicin + PTT vs PTT[15-18,20] (PP)	80.65	68.57	0	0.513	1.93	1.25-2.96	0.003
Allicin-PPI-B-T-C vs PPI-B-T-C[21,22] (ITT/PP)	95.51	87.82	22.924	0.255	2.83	1.13-7.10	0.026
Allicin-PPI-Am-F vs PPI-Am-F[15,18,20] (ITT/PP)	83.62	65.00	0	0.660	1.90	1.18-3.06	0.002

PPI: Proton pump inhibitor; PTT: Proton pump inhibitor triple therapy; Am: Amoxicillin; F: Furazolidone; C: Clarithromycin; T: Tinidazole; B: Bismuth potassium citrate tablets; ITT: Intent-to-treat analysis; PP: Pre-protocol analysis; OR: Odds ratio; CI: Confidence interval.

Citation: Si XB, Zhang XM, Wang S, Lan Y, Zhang S, Huo LY. Allicin as add-on therapy for Helicobacter pylori infection: A systematic review and meta-analysis. World J Gastroenterol 2019; 25(39): 6025-6040
URL: https://www.wjgnet.com/1007-9327/full/v25/i39/6025.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i39.6025