Prevalence of hepatocarcinoma-related hepatitis B virus mutants in patients in grey zone of treatment

Figure 4 Analysis of preS deletion mutations related with the hepatocellular carcinoma risk. A: Frequency of coexistence of hepatocellular carcinoma related mutations in both BCP/precore and preS regions (Dark bars indicate the patients with theoretical highest risk of hepatocellular carcinoma development, based in the coexistence of mutations in the HBsAg and precore region, or the simultaneous detection of 3 or more mutation irrespective of the genomic region); B: Prevalence of preS deletions in different genotypes and ethnic groups. Only a Caucasian patient infected with HBV-H genotype had a preS1 deletion. BCP: Basal core promoter.