Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis

doi:10.3748/wjg.v25.i38.5800

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Oct 14, 2019 (publication date) through Jan 5, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 14, 2019; 25(38): 5800-5813
Published online Oct 14, 2019. doi: 10.3748/wjg.v25.i38.5800

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Figure 7 SIRT1 activation reduces apoptotic cell rates in dextran sodium sulfate-induced colitis. A: TUNEL staining of colon tissue was performed; B: The number of TUNEL positive cells per 10000 cells was counted. Each value is presented as the mean ± SD. ^bP < 0.01 vs UC; ^cP < 0.001 vs UC; ^dP < 0.001 vs control. TUNEL: Transferase-mediated dUTP nick-end labeling; UC: Ulcerative colitis; NAM: Nicotinamide.

Citation: Ren MT, Gu ML, Zhou XX, Yu MS, Pan HH, Ji F, Ding CY. Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis. World J Gastroenterol 2019; 25(38): 5800-5813
URL: https://www.wjgnet.com/1007-9327/full/v25/i38/5800.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i38.5800