Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis

Figure 6 SIRT1 decreases inflammatory cytokine expression in dextran sodium sulfate-induced colitis. The expression levels of IL-1β and TNF-α were detected by ELISA. A: The expression of IL-1β in colon tissues; B: The expression of TNF-α in colon tissues. Data are presented as the mean ± SD. ^aP < 0.05 vs UC; ^bP < 0.01 vs UC; ^cP < 0.001 vs UC; ^dP < 0.001 vs control. UC: Ulcerative colitis; NAM: Nicotinamide; IL-1β: interleukin-1β; TNF-α: Tumor necrosis factor-α; ELISA: Enzyme-linked immunosorbent assay.