Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil

Table 5 Utilization of healthcare resources during the retrospective 3-year period

	CD				UC
	Total	Moderate to severe activity	No or mild activity	P value	Total	Moderate to severe activity	No or mild activity	P value
n	264	118	146		143	36	107
IBD surgeries
At least one IBD surgery	67 (25.4)	32 (27.1)	35 (24.0)	0.559 1	4 (2.8)	1 (2.8)	3 (2.8)	--
Surgeries, n	108	45	63		7	2	5
Surgeries/pt, median [range]	1.0 [1-5]	1.0 [1-4]	2 [1-5]	0.074	2.0 [1-2]	2	2.0 [1-2]	--
More than one IBD surgery	28 (41.8)	10 (31.2)	18 (51.5)		3 (75.0)	1 (100.0)	2 (66.7)
Type [frequency ≥ 5%]
Partial colectomy	13 (12.0)	5 (11.1)	8 (12.7)		0 (0.0)	0 (0.0)	0 (0.0)
Total colectomy	1 (0.9)	0 (0.0)	1 (1.6)		2 (28.6)	1 (50.0)	1 (20.0)
Drainage of anorectal abscess	6 (5.6)	3 (6.7)	3 (4.8)		0 (0.0)	0 (0.0)	0 (0.0)
Fistulectomy	22 (20.4)	9 (20.0)	13 (20.6)		0 (0.0)	0 (0.0)	0 (0.0)
Enterostomy	13 (12.0)	6 (13.3)	7 (11.1)		0 (0.0)	0 (0.0)	0 (0.0)
Enterostomy closure	5 (4.6)	5 (11.1)	0 (0.0)		2 (28.6)	0 (0.0)	2 (40.0)
IBD hospitaliza-tions
At least one IBD hospitaliza-tion	101 (38.3)	51 (43.2)	50 (34.2)	0.136 1	28 (19.6)	11 (30.6)	17 (15.9)	0.055 1
Hospitaliza-tions, n	168	93	75		43	18	25
Hospitaliza-tions/pt, median [range]	1.0 [1-5]	2.0 [1-4]	1.0 [1-5]	0.031	1.0 [1-5]	1.0 [1-5]	1.0 [1-3]	0.978
More than one hospitalization	47 (46.5)	29 (56.8)	18 (36.0)		10 (35.7)	4 (36.4)	6 (35.3)
Duration (d), median [range]	6 [1-98]	5 [0-76]	4.5 [0-97]		4 [1-737]	2.5 [0-20]	5 [0-737]
IBD medical appointments
At least one IBD consultation	263 (99.6)	117 (99.2)	146 (100.0)		143 (100.0)	36 (100.0)	107 (100.0)
Consultations, n	3192	1466	1726		1541	423	1118
Consultations /pt, median [range]	11.0 [1-45]	12.0 [1-45]	11.0 [1-35]	0.801	10.0 [1-39]	9.5 [1-39]	10.0 [2-30]	0.896
More than 20 consultations	27 (10.3)	15 (12.8)	12 (8.2)		9 (6.3)	4 (11.1)	5 (4.7)
Type
IBD specialist	2989 (93.6)	1356 (92.4)	1633 (94.6)		1426 (92.5)	394 (93.1)	1032 (92.3)
Emergency	43 (1.3)	25 (1.7)	18 (1.0)		34 (2.2)	20 (4.7)	14 (1.3)
Other specialist	160 (5.0)	85 (5.8)	75 (4.3)		81 (5.3)	9 (2.1)	72 (6.4)
Consultations with registered score
HBI	11 (0.3)	1 (0.1)	10 (0.6)		--	--	--
CDAI	103 (3.2)	54 (3.7)	49 (2.8)		--	--	--
Other CD scores	30 (0.9)	21 (1.4)	9 (0.5)		--	--	--
pMayo score	--	--	--		95 (6.2)	12 (2.8)	83 (7.4)
Consultations with change of IBD treatment	522 (16.4)	269 (18.3)	253 (14.7)	0.005 1	353 (22.9)	86 (20.3)	267 (23.9)	0.139 1
IBD imaging and laboratory testing
At least one IBD test	260 (98.5)	116 (98.3)	144 (98.6)	--	141 (98.6)	36 (100.0)	105 (98.1)	--
IBD tests, n	5674	2722	2952		2509	643	1866
Tests/pt, median [range]	19.0 [1-143]	20.0 [1-143]	16.0 [1-94]	0.372	15.0 [1-82]	14.5 [2-82]	16 [1-75]	0.767
More than 20 tests	118 (45.4)	56 (48.3)	62 (43.1)		57 (40.4)	15 (41.7)	42 (40.0)
Type [frequency ≥ 5%]
Complete blood cell count	2317 (40.8)	1077 (39.6)	1240 (42.0)		973 (38.8)	250 (38.9)	723 (38.7)
C-reactive protein	1773 (31.2)	837 (30.7)	936 (31.7)		748 (29.8)	214 (33.3)	534 (28.6)
Serum albumin	647 (11.4)	346 (12.7)	301 (10.2)		356 (14.2)	59 (9.2)	297 (15.9)
Colonoscopy	346 (6.1)	183 (6.7)	163 (5.5)		228 (9.1)	57 (8.9)	171 (9.2)

All P-values from Mann-Whitney U test, except

¹Chi-square test. Data are shown as n (%), except otherwise mentioned. CD: Crohn’s disease; UC: Ulcerative colitis; IBD: Inflammatory bowel disease; pt: Patient.