Hepatitis C virus clearance and less liver damage in patients with high cholesterol, low-density lipoprotein cholesterol and APOE ε4 allele

Table 5 Receiver operating characteristic analysis of variables associated with spontaneous hepatitis C virus clearance

Variable	Cutoff	AUC	P value	Sensitivity, %	Specificity, %	PPV	NPV
ALT, IU/L	50.5	.79	< 0.001	62%	83%	88%	52%
LDL-c, mg/dL	101.5	.72	< 0.001	60.7%	78%	79%	58%
Triglycerides, mg/dL	117.5	.64	< 0.001	69%	55%	78%	42%
BMI, kg/m2	26.6	.59	0.018	63%	54%	76%	38.7%

PPV: Positive predictive value; NPV: Negative predictive value; AUC: Area under the curve; ALT: Alanine transaminase; LDL-c: Low-density lipoprotein cholesterol; BMI: Body mass index.