Post-transplant infection improves outcome of hepatocellular carcinoma patients after orthotopic liver transplantation

Table 2 Univariate analysis of overall and recurrence-free survival of transplant hepatocellular carcinoma patients

Variable	Overall survival		Recurrence-free survival
	χ2	P-value	χ2	P-value
Age (≤ 50 vs > 50)	2.828	0.093	1.682	0.195
Sex (male vs female)	0.011a	0.916	-0.020	0.888
Liver cirrhosis (no vs yes)	8.361	0.004b	5.429	0.020a
Pre-operative AFP level (≥ 200 ng/mL vs < 200 ng/mL)	9.938	0.002b	8.879	0.003b
Child-Pugh score (A/B/C)	1.609	0.447	1.020	0.600
HBsAg (positive vs negative)	0.512	0.474	0.349	0.555
HBeAg (positive vs negative)	0.253	0.615	0.412	0.521
Tumor number (multiple vs single)1	0.800	0.371	2.027	0.155
Tumor size (> 5 cm vs ≤ 5 cm)1	37.554	< 0.001c	45.365	< 0.001c
Histological grade (G3-G4 vs G1-G2)1	12.165	< 0.001c	14.790	< 0.001c
Vascular invasion (yes vs no)1	32.767	< 0.001c	45.440	< 0.001c
Lymphnode involvement (yes vs no)1	12.750	< 0.001c	25.258	< 0.001c
Pathological TNM stage (III vs I/II)1	17.938	< 0.001c	30.984	< 0.001c
PTI (without vs with)	4.554	0.033a	3.463	0.063

¹Data explored by histological examination. AFP: Alpha fetoprotein; PTI: Post-transplant infection.

^aP < 0.05;

^bP < 0.01;

^cP < 0.001.