Diagnostic value of gamma-glutamyltransferase/aspartate aminotransferase ratio, protein induced by vitamin K absence or antagonist II, and alpha-fetoprotein in hepatitis B virus-related hepatocellular carcinoma

Figure 3 Correlations of serum levels of protein induced by vitamin K absence or antagonist II, alpha-fetoprotein, and the ratio of gamma-glutamyltransferase to aspartate aminotransferase with hepatitis B virus DNA. A-C: Comparisons of serum levels of protein induced by vitamin K absence or antagonist II (PIVKA-II), alpha-fetoprotein (AFP), and the ratio of gamma-glutamyltransferase to aspartate aminotransferase (γ-GT/AST) between hepatitis B virus (HBV) DNA+ and HBV DNA- hepatocellular carcinoma (HCC) patients; D-F: Comparisons of serum levels of PIVKA-II, AFP, and γ-GT/AST between HBV DNA+ and HBV DNA- chronic hepatitis B patients. G-I: Correlations of PIVKA-II, AFP, and γ-GT/AST with serum levels of HBV DNA in HBV DNA+ HCC patients. PIVKA-II: Protein induced by vitamin K absence or antagonist II; AFP: Alpha-fetoprotein; γ-GT/AST: The ratio of gamma-glutamyltransferase to aspartate aminotransferase; HBV: Hepatitis B virus; HCC: Hepatocellular carcinoma; CHB: Chronic hepatitis B.