Diagnostic value of gamma-glutamyltransferase/aspartate aminotransferase ratio, protein induced by vitamin K absence or antagonist II, and alpha-fetoprotein in hepatitis B virus-related hepatocellular carcinoma

Figure 2 Receiver-operating characteristic curves of protein induced by vitamin K absence or antagonist II, alpha-fetoprotein, the ratio of gamma-glutamyltransferase to aspartate aminotransferase, and their combinations in hepatocellular carcinoma patients. A and B: Receiver-operating characteristic (ROC) curves of protein induced by vitamin K absence or antagonist II (PIVKA-II), alpha-fetoprotein (AFP), the ratio of gamma-glutamyltransferase to aspartate aminotransferase (γ-GT/AST), and their combinations in early-stage hepatocellular carcinoma (HCC) patients; chronic hepatitis B patients (CHB) served as controls; C and D: ROC curves of PIVKA-II, AFP, γ-GT/AST, and their combinations in HCC patients; CHB patients served as controls. ROC curve: Receiver-operating characteristic curve; PIVKA-II: Protein induced by vitamin K absence or antagonist II; AFP: Alpha-fetoprotein; γ-GT/AST: The ratio of gamma-glutamyltransferase to aspartate aminotransferase; HCC: Hepatocellular carcinoma; CHB: Chronic hepatitis B.