CARMA3/NF-κB signaling contributes to tumorigenesis of hepatocellular carcinoma and is inhibited by sodium aescinate

Figure 1 CARMA3 and nuclear factor kappa-B (p65) are correlated with clinical prognosis in hepatocellular carcinoma patients. A: High CARMA3 (n = 54) expression suggested shorter overall survival time (P = 0.027); B: High nuclear factor kappa-B (NF-κB) (p65) (n = 40) expression indicated shorter postoperative overall survival (P = 0.005); C: Hepatocellular carcinoma (HCC) patients with high CARMA3 expression had a shorter disease free survival time than those with low CARMA3 expression (P = 0.007); D: Correlation between CARMA3 and NF-κB expression in HCC tissue (P = 0.002). NF-κB: Nuclear factor kappa-B.