LncRNA-ATB promotes autophagy by activating Yes-associated protein and inducing autophagy-related protein 5 expression in hepatocellular carcinoma

Figure 6 Yes-associated protein nuclear localization and autophagy-related protein 5 expression are positively correlated with lncRNA-ATB expression. A: Representative immunostaining for Yes-associated protein (YAP) in hepatocellular carcinoma (HCC) and adjacent normal tissues (magnification: ×200 or ×400); B: The expression levels of autophagy-related protein 5 (ATG5) in 72 pairs of HCC tumor and adjacent normal tissues were evaluated by real-time PCR; C: Pearson’s correlation analysis of the relationship between expression of lncRNA-ATB and ATG5 (r = 0.527, P < 0.001). Statistical significance is indicated at ^bP < 0.01. YAP: Yes-associated protein; ATG5: Autophagy-related protein 5; HCC: Hepatocellular carcinoma; LncRNA-ATB: LncRNA-activated by transforming growth factor beta.