Long non-coding RNA highly up-regulated in liver cancer promotes exosome secretion

Figure 7 Increased long non-coding RNA highly up-regulated in liver cancer and Rab11a and decreased miR-372-3p promote the secretion of exosomes from hepatocellular carcinoma cells. A: Quantification of exosomes after transfecting HULC over-expression plasmid into HCC cells; B: Quantification of exosomes after transfecting miR-372-3p low-expression plasmid into HCC cells; C: Quantification of exosomes after transfecting Rab11a over-expression plasmid into HCC cells. Error bars stand for the mean ± SD of at least triplicate experiments. ^aP < 0.01 vs NC group; ^bP < 0.01 vs HULC-NC group; ^cP < 0.01 vs NC group; ^dP < 0.01 vs miRNA-372-3p-siRNA-NC group; ^eP < 0.01 vs NC group; ^fP < 0.01 vs Rab11a-NC group. HULC: Highly upregulated in liver cancer; HULC: HULC over-expression group; HULC-NC: HULC (over-expression plasmid normal control group); NC: Normal control; miR-372-3p-siRNA: miR-372-3p low-expression group; miR-372-3p-siRNA-NC: miR-372-3p low-expression plasmid normal control group; Rab11a: Rab11a over-expression group; Rab11a-NC: Rab11a over-expression plasmid normal control group.