Long non-coding RNA highly up-regulated in liver cancer promotes exosome secretion

Figure 3 Detection of long non-coding RNA highly up-regulated in liver cancer in hepatocellular carcinoma cells. A:Expression of HULC in HepG2, SMMC7721, and LO2 cells; B: Expression of HULC in HepG2 transfected with HULC inhibitors or plasmids causing HULC overexpression; C: Expression of HULC in SMMC7721 transfected with HULC inhibitors or plasmids causing HULC overexpression. Error bars stand for the mean ± SD of at least triplicate experiments. ^aP < 0.05 vs LO2 group; ^bP < 0.05 vs LO2 group; ^cP < 0.01 vs NC group; ^dP < 0.01 vs HULC-NC group; ^eP < 0.05 vs NC group; ^fP < 0.05 vs HULC-siRNA-NC group. HULC: Highly upregulated in liver cancer; NC: Normal control group; HULC: HULC over-expression plasmid group; HULC-NC: HULC over-expression normal control plasmid group; HULC-siRNA: HULC low-expression plasmid group; HULC-siRNA-NC: HULC low-expression control plasmid group.