Pathological response measured using virtual microscopic slides for gastric cancer patients who underwent neoadjuvant chemotherapy

Table 3 Comparison of prognostic utility of 10% cut-off evaluated using virtual microscopic slides with JCGC criteria

Histological criteria of JCGC	RFS		OS
	HR (95%CI)	P value	HR (95%CI)	P value
Grade 0 vs 1a–3	0.52 (0.15–1.80)	0.304	2.27 (0.27–19.0)	0.449
Grade 0–1a vs 1b–3	0.63 (0.26–1.55)	0.321	0.72 (0.26–1.95)	0.52
Grade 0–1b vs 2–3	0.33 (0.12–0.87)	0.026	0.39 (0.13–1.15)	0.089
Grade 0–2 vs 3	0.69 (0.08–5.34)	0.722	0.62 (0.07–5.34)	0.665
Our method
Responder vs non-responder	0.29 (0.10–0.82)	0.019	0.23 (0.07–0.78)	0.018

NAC: Neoadjuvant chemotherapy; HR: Hazard ratio; JCGC: Japanese Classification of Gastric Carcinoma; CI: Confidence interval; RFS: Relapse-free survival; OS: Overall survival.