Liver stiffness and serum markers for excluding high-risk varices in patients who do not meet Baveno VI criteria

Table 3 Performance of liver stiffness measurement and serum markers of liver fibrosis in predicting high-risk varices in patients who did not meet the 2015 Baveno VI criteria

Variable	AUROC (95%CI)	P-value	Cutoffvalue	Se (%)	Sp (%)	PPV (%)	PLR	Spared gastroscopies, n = 132, (%)
LSM	0.637 (0.548-0.718)	0.0141	20.9	100	29.52	26.7	1.42	31/132 (23.5)
PLT	0.712 (0.627-0.787)	< 0.0001	151.0	100	9.52	22.1	1.11	10/132 (7.6)
Lok index	0.753 (0.671-0.824)	< 0.0001	0.4531	100	30.48	27.0	1.44	32/132 (24.2)
MELD	0.644 (0.556-0.726)	0.0122	6.0	100	6.67	21.6	1.07	7/132 (5.3)
APRI	0.586 (0.497-0.671)	0.1453
FIB-4	0.585 (0.496-0.670)	0.1281

APRI: Aspartate aminotransferase-to-platelet ratio index; AUROC: Area under the receiver operating characteristic curve; CI: Confidence interval; MELD: Model for End-Stage Liver Disease; PLT: Platelet; PLR: Positive likelihood ratio; PPV: Positive predictive value; Se: Sensitivity; Sp: Specificity. P < 0.05 was statistically significant.