Timing, distribution, and microbiology of infectious complications after necrotizing pancreatitis

Table 5 Multivariable analysis for independent predictors of mortality

Variable	Univariable analysis	P-value	Multivariable analysis	P-value
	OR (95%CI)		OR (95%CI)
Persistent OF	5.37 (3.785-7.618)	< 0.001	0.012 (0.001-0.101)	< 0.001c
MDR organism (s)	2.445 (1.554-3.848)	0.001	0.134 (0.028-0.633)	0.011b
Fungal infection	2.719 (1.498-4.936)	0.002	0.657 (0.156-2.770)	0.567
Prophylactic antibiotic	0.974 (0.783-1.210)	0.8	0.534 (0.095-2.989)	0.475
INP	1.151 (0.802-1.651)	0.48	0.277 (0.024-3.234)	0.306
Extrapancreatic infection	1.383 (1.124-1.704)	0.031	0.627 (0.042-9.273)	0.734
Referred patients	1.102 (0.986-1.232)	0.25	0.524 (0.041-6.655)	0.619
Operation	0.789 (0.497-1.255)	0.262	10.533 (1.052-105.491)	0.045a
Complication	2.921 (1.304-6.540)	0.011	0.892 (0.191-4.162)	0.885

^aP < 0.05,

^bP < 0.01,

^cP < 0.001. OF: Organ failure; INP: Infectious necrotizing pancreatitis; TPN: Total parenteral nutrition; EN: Enteral nutrition; CI: Confidence interval; OR: Odds ratio; MDR: Multidrug-resistant.