Copyright
©The Author(s) 2019.
World J Gastroenterol. Sep 14, 2019; 25(34): 5152-5161
Published online Sep 14, 2019. doi: 10.3748/wjg.v25.i34.5152
Published online Sep 14, 2019. doi: 10.3748/wjg.v25.i34.5152
Table 2 Single nucleotide polymorphism and genotype distribution between gastric cancer cases and controls
SNP | Genotype | Case | Control | HWE | P-value | OR | 95%CI | P-value | OR1 | 95%CI | P-value |
n = 956 | n = 1012 | ||||||||||
Rs2094258 | CC | 390 (40.8) | 437 (43.2) | 0.318 | 0.853 | 1.00 | |||||
CT | 441 (46.1) | 464 (45.8) | 1.07 | 0.88-1.29 | 0.545 | 1.05 | 0.86-1.31 | 0.626 | |||
TT | 125 (13.1) | 111 (11.0) | 1.26 | 0.94-1.69 | 0.133 | 1.19 | 0.90-1.20 | 0.249 | |||
Dominant | 566 (59.2) | 575 (56.8) | 1.10 | 0.92-1.32 | 0.284 | 1.06 | 0.87-1.37 | 0.388 | |||
Recessive | 831 (86.9) | 901 (89.0) | 1.22 | 0.93-1.60 | 0.150 | 1.19 | 0.91-1.72 | 0.303 | |||
Rs751402 | CC | 366 (38.3) | 371 (36.7) | 0.183 | 0.913 | 1.00 | |||||
CT | 467 (48.8) | 476 (47.0) | 0.95 | 0.78-1.16 | 0.618 | 0.98 | 0.77-1.33 | 0.774 | |||
TT | 123 (12.9) | 165 (16.3) | 0.88 | 0.67-1.15 | 0.341 | 0.90 | 0.61-1.28 | 0.491 | |||
Dominant | 590 (61.7) | 632 (62.5) | 0.95 | 0.79-1.14 | 0.554 | 0.95 | 0.78-1.22 | 0.711 | |||
Recessive | 833 (87.1) | 847 (83.7) | 0.90 | 0.71-1.15 | 0.411 | 0.93 | 0.69-1.18 | 0.487 | |||
Rs2296147 | TT | 599 (62.7) | 640 (63.2) | 0.076 | 0.963 | 1.00 | |||||
CT | 301 (31.5) | 332 (32.9) | 0.97 | 0.80-1.17 | 0.745 | 0.97 | 0.80-1.19 | 0.674 | |||
CC | 56 (5.9) | 40 (3.9) | 1.50 | 0.98-2.28 | 0.059 | 1.40 | 0.97-2.50 | 0.061 | |||
Dominant | 357 (37.3) | 372 (36.8) | 1.03 | 0.85-1.23 | 0.789 | 1.01 | 0.80-1.38 | 0.865 | |||
Recessive | 900 (94.1) | 973 (96.1) | 1.51 | 1.00-2.29 | 0.050 | 1.36 | 0.99-2.49 | 0.053 | |||
Rs1047768 | TT | 505 (52.8) | 540 (53.4) | 0.367 | 0.832 | 1.00 | |||||
CT | 379 (39.6) | 406 (40.1) | 1.00 | 0.83-1.20 | 0.985 | 1.00 | 0.80-1.28 | 0.989 | |||
CC | 72 (7.6) | 66 (6.5) | 1.17 | 0.82-1.66 | 0.395 | 1.11 | 0.79-1.92 | 0.505 | |||
Dominant | 451 (47.2) | 472 (46.6) | 1.02 | 0.86-1.22 | 0.812 | 1.01 | 0.81-1.45 | 0.897 | |||
Recessive | 884 (92.5) | 946 (93.5) | 1.17 | 0.83-1.65 | 0.381 | 1.12 | 0.74-1.84 | 0.561 | |||
Rs873601 | GG | 271 (28.3) | 288 (28.5) | 0.247 | 0.884 | 1.00 | |||||
AG | 475 (49.7) | 514 (50.8) | 0.98 | 0.80-1.21 | 0.865 | 0.99 | 0.63-1.88 | 0.931 | |||
AA | 210 (22.0) | 210 (20.7) | 1.06 | 0.83-1.37 | 0.638 | 1.03 | 0.71-2.01 | 0.807 | |||
Dominant | 685 (71.7) | 724 (71.5) | 1.12 | 0.92-1.37 | 0.245 | 1.07 | 0.82-1.94 | 0.466 | |||
Recessive | 746 (78.0) | 802 (79.2) | 1.08 | 0.87-1.33 | 0.511 | 0.98 | 0.88-1.37 | 0.685 |
- Citation: Wang XQ, Terry PD, Li Y, Zhang Y, Kou WJ, Wang MX. Association of XPG rs2094258 polymorphism with gastric cancer prognosis. World J Gastroenterol 2019; 25(34): 5152-5161
- URL: https://www.wjgnet.com/1007-9327/full/v25/i34/5152.htm
- DOI: https://dx.doi.org/10.3748/wjg.v25.i34.5152