Regulatory effect of a Chinese herbal medicine formula on non-alcoholic fatty liver disease

doi:10.3748/wjg.v25.i34.5105

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 14, 2019; 25(34): 5105-5119
Published online Sep 14, 2019. doi: 10.3748/wjg.v25.i34.5105

Table 8 Effect of Chinese herbal medicine on liver tissue TNF-α, TGF-β1, NF-kB, and TLR4 levels (mean ± SD)

Group	n	TNF-α (ng/mg)	TGF-β1 (ng/mg)	NF-kB (ng/mg)	TLR4 (ng/mg)
Control	8	5.35 ± 0.80	2.21 ± 0.43	10.87 ± 2.45	21.32 ± 1.87
Model	8	7.22 ± 0.81^b	3.01 ± 0.22^b	15.85 ± 2.50^b	30.28 ± 4.38^b
PH	8	5.48 ± 0.38^d	2.24 ± 0.26^d	12.15 ± 3.13^c	22.56 ± 3.02^d
CHM	8	6.01 ± 0.97^d	2.29 ± 0.40^d	12.57 ± 3.30	23.88 ± 3.21^d

^bP < 0.01 vs control group;

^cP < 0.05,

^dP < 0.01 vs model group. TGF-β1: Transforming growth factor-β1; TNF-α: Tumor necrosis factor-α; TLR4: Toll-like receptor-4; NF-kB: Nuclear factor-kappa B; PH: Pioglitazone hydrochloride; CHM: Chinese herbal medicine.

Citation: Yang JM, Sun Y, Wang M, Zhang XL, Zhang SJ, Gao YS, Chen L, Wu MY, Zhou L, Zhou YM, Wang Y, Zheng FJ, Li YH. Regulatory effect of a Chinese herbal medicine formula on non-alcoholic fatty liver disease. World J Gastroenterol 2019; 25(34): 5105-5119
URL: https://www.wjgnet.com/1007-9327/full/v25/i34/5105.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i34.5105