Lymphocyte-to-monocyte ratio effectively predicts survival outcome of patients with obstructive colorectal cancer

Figure 2 Receiver operating characteristic curve and long-term survival analysis of emergency surgery and bridge to surgery group. Derived neutrophil-to-lymphocyte ratio (dNLR) is preferred as a prognostic biomarker for the emergency surgery (ES) group with the highest area under receiver operating characteristic curve (AUC) for 3-year overall survival (OS) (0.679, 95%CI: 0.551-0.808) (A) and 3-year disease-free survival (DFS) (0.679, 95%CI: 0.551-0.808) (B), with a cutoff point value of 1.57. High-ratio grade of dNLR (≥ 1.57) was closely related to lower 3-year DFS (≥ 1.57 vs <1.57, 23.10 ± 13.85 mo vs 31.45 ± 9.35 mo, P = 0.009) in the ES group (D), but not with 3-year OS (C). Lymphocyte-to-monocyte ratio (LMR) was preferred as a prognostic biomarker for bridge to surgery (BTS) group with the highest AUC for 3-year OS (0.611, 95%CI: 0.424-0.798) (E) and 3-year DFS (0.571, 95%CI: 0.366-0.776) (F), with a cutoff point value of 1.67. High-ratio grade of LMR (≥ 1.67) was closely related to lower 3-year OS (≥ 1.67 vs <1.67, 23.10 ± 13.85 mo vs 33.78 ± 5.35 mo, P = 0.020) (G) and 3-year DFS (≥ 1.67 vs < 1.67, 22.67 ± 14.02 mo vs 31.50 ± 8.89 mo, P = 0.046) in the BTS group (H).