Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source

Figure 5 Liver histopathological scores and collagen 1a1 deposition in C57BL/6J mice fed chow, amylin liver non-alcoholic steatohepatitis (AMLN) or Gubra amylin non-alcoholic steatohepatitis (GAN) diet for 28 wk. A: Steatosis; B: Lobular inflammation; C: Hepatocyte ballooning; D: Non-alcoholic fatty liver disease activity score (NAS); E: Fibrosis score; F: Collagen-1a1 fractional area (mean ± SEM). ^cP < 0.001 vs chow-fed C57BL/6J (Chow C57) mice. AMLN: Amylin liver non-alcoholic steatohepatitis diet; GAN: Gubra amylin non-alcoholic steatohepatitis diet; NASH: Non-alcoholic steatohepatitis.