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©The Author(s) 2019.
World J Gastroenterol. Sep 7, 2019; 25(33): 4933-4944
Published online Sep 7, 2019. doi: 10.3748/wjg.v25.i33.4933
Published online Sep 7, 2019. doi: 10.3748/wjg.v25.i33.4933
Table 3 Hospital admissions for hepatic decompensation for proton pump inhibitor users and non-users with decompensated liver cirrhosis
| Number of patients | Hospital admissions for liver decompensation | ||
| Adjusted RR (95%CI) | P value | ||
| Entire cohort | PPI user = 335 Non-user = 116 | 1.61 (1.30-2.11) | < 0.001 |
| Dose exposure | |||
| Non-user | 116 | Ref | |
| cDDD 28-90 | 49 | 0.65 (0.39-1.08) | 0.10 |
| cDDD 91-180 | 61 | 1.08 (0.74-1.59) | 0.69 |
| cDDD > 180 | 225 | 1.91 (1.49-2.45) | < 0.001 |
- Citation: De Roza MA, Kai L, Kam JW, Chan YH, Kwek A, Ang TL, Hsiang JC. Proton pump inhibitor use increases mortality and hepatic decompensation in liver cirrhosis. World J Gastroenterol 2019; 25(33): 4933-4944
- URL: https://www.wjgnet.com/1007-9327/full/v25/i33/4933.htm
- DOI: https://dx.doi.org/10.3748/wjg.v25.i33.4933