Helicobacter pylori virulence genes

Table 1 Prevalence of oipA “on” status among isolates from various geographical regions

Country	Number of patients	Study population	oipA “on” prevalence	Association with other virulence genes
North-Eastern Brazil[30]	95	Adults with gastritis, GC and their first degree relatives, asymptomatic children	81.1%	cagAvacA s1 m1
Iran[31]	53	Adults and children with chronic gastritis, PUD, intestinal metaplasia and GC	79.0%	cagA, vacA s1 m1
Venezuela[32]	113	Adults with chronic gastritis	83.0%	NA
Bulgaria[33]	70	Symptomatic adults	81.0%	cagA, vacA s1, m1 and m2
Malaysia and Singapore[34]	159	Adults with functional dyspepsia, GC and PUD	89.4%	vacA m1/m2
Italy[35]	90	Adults with chronic gastritis and PUD	77.4%	babA2, hopQ
Colombia and United States[36]	200	Patients with gastritis, PUD and GC	79.3%	cagA, babA
Germany[26]	58	Patients with chronic gastritis	59.0%	cagA, vacA s1, babA
Netherlands[37]	96	Adults with chronic gastritis, PUD, GC and lymphoma	72.0%	cag PAI+
Italy[27]	60	Adults with chronic gastritis, PUD and duodenitis	60.0%	cagA, vacA s1 and m1, babA
East Asia and India[38]	54	Adults with gastritis and PUD	100.0%	cagA, vacA s1
Western countries[38]	55	Adults with gastritis and PUD	63.6%	cagA, vacA s1

NA: Not available; PUD: Peptic ulcer disease; GC: Gastric cancer.