Positron-emission tomography for hepatocellular carcinoma: Current status and future prospects

Figure 2 ¹¹C-choline positron-emission tomography-computed tomography detected a tumor that was missed on conventional 2-deoxy-2-(¹⁸F)fluoro-D-glucose positron-emission tomography-computed tomography in a 58-year-old patient with hepatocellular carcinoma. A-D: 2-deoxy-2-(¹⁸F)fluoro-D-glucose positron-emission tomography-computed tomography (¹⁸F-FDG PET-CT) showed that there was no increased ¹⁸F-FDG uptake in the liver; E-H: ¹¹C-choline (¹¹C-CHOL) PET-CT showed focal increased ¹¹C-CHOL uptake in the upper segment of the anterior lobe of the liver, and the size of the lesion was 1.2 × 1.3 cm (blue arrow in F and G). Pathological examination confirmed well-differentiated hepatocellular carcinoma. ¹⁸F-FDG: 2-deoxy-2-(¹⁸F)fluoro-D-glucose; CT: Computed tomography; PET: Positron-emission tomography; ¹¹C-CHOL: ¹¹C-choline.