Liver cirrhosis and left ventricle diastolic dysfunction: Systematic review

Table 1 Included studies and patients’ characteristics

Author	Study type	Number of cases, n	Gender (male), n	Control, n	Etiology of cirrhosis, n			Means1 of Child-Pugh scores'	Child-Pugh classification, n			Means1 of MELD scores'
					V	A	O		A	B	C
Dadhich et al[31]	Cross sectional case control study	40	ND	20	26	10	4	7.5 ± 1.08 pre-ascitic group, 9.4 ± 2.11 ascitic group	4	22	14	ND
Lee et al[32]	Cohort study	70	55	0	16	47	7	ND	18	35		14.1 ± 5.9
Karagiannakis et al[33]	Cohort study	45	E33	0	19	22	4	6.43 ± 1.9	26	15	3	11.5 ± 4.2
Alexopoulou et al[34]	Cross-sectional observa-tional study	76	57	0	41	20	15	9.2 ± 2.7	11	28	37	17 ± 7
Farouk et al[15]	Cross-sectional study	35	22	16	35			ND	6	14	15	ND
Bhuin et al[16]	Descrip-tive study	70	32	0			70	ND	4	38	28	ND
Cesari et al[35]	Case series	117	106	46		57	60	8 ± 2	ND	ND	ND	12 ± 5
Ru ız-del- Arbol, et al[21]	Cross-sectional	80	67	0	32	35	13	8 ± 2 grade 0; 9 ± 2 grade 1; 10 ± 2 grade 2;	12	30	38	15 ± 6 grade 0; 16 ± 5 grade 1; 21 ± 6 grade 2;
Rimbas et al[36]	Cross-sectional observa-tional study	46	30	46	19	24	3	7 ± 2	23	16	7	13 ± 5
Hammami et al[25]	Cross-sectional study	80	42	80	42		38	ND	24	36	20	14.2 ± 4.98
Merli et al[37]	Cross-sectional observa-tional study	90	59	31	49	28	13	ND	48	26	16	11.9 ± 4.7
Merli et al[26]	Case series	74	44	26	41	21	12	ND	29	26	19	13 ± 5
Kazankov et al[38]	Cross-sectional observa-tional study	44	27	23	5	32	7	7.1 ± 2.2	20	12	8	12.3 ± 4.9
Nazar et al[22]	Case series	100	71	0	41	46	15	with LVDD 9 ± 2; no LVDD 8 ± 2.2	26	39	37	15 ± 7
Devauchelle et al[39]	Descrip-tive study	40	30	0	9	24	7	ND	13	9	18	16
Somani et al[24]	Cross-sectional observa-tional study	60	48	30	22	30	8	ND	8	26	26	15.2 ± 4.6 without LVDD;14.6 ± 4.3 with LVDD
Total		1067	723	318

¹Values are expressed as mean ± standard deviation. V: Viral; A: Alcoholic; O: Other; ND: No data.