Review of current diagnostic methods and advances in Helicobacter pylori diagnostics in the era of next generation sequencing

Table 1 Who to test, summary of the recommendations from the fifth Maastricht/Florence consensus report[23]

Recommendations from the fifth Maastricht/Florence consensus report
Dyspepsia	Subject to regional Helicobacter pylori prevalence, not applicable to patients with alarm symptoms or older patients
Peptic ulcers	Especially in aspirin and nonsteroidal anti-inflammatory drugs users with history of peptic ulcer
Gastritis	Especially in long-term proton-pump-inhibitor users
Gastric cancer	In individuals at increased risk of gastric cancer
MALToma	In individuals with localized early-stage MALToma
Iron deficiency anemia, idiopathic thrombocytopenic purpura, vitamin B12 deficiency