Common features between neoplastic and preneoplastic lesions of the biliary tract and the pancreas

Figure 3 Common and distinctive features of pancreatic and biliary intraductal papillary mucinous neoplasms. Low power view of intraductal papillary mucinous neoplasm of the pancreas (A) with oncocytic aspects (B), causing evident dilatation of the Wirsung duct which was detected radiologically as a macroscopic lesion. Low power view of intraductal papillary neoplasm of the bile duct (C) characterized by a polypoid growth inside the common hepatic duct, composed of multiple papillary projections with a fibrovascular stroma and covered by oncocytic cells (D). In the upper left part of panel D at higher magnification, the transition between the normal bile duct epithelium and the papillary neoplastic proliferation is evident.