Layered enhancement at magnetic resonance enterography in inflammatory bowel disease: A meta-analysis

Table 1 Study and patient characteristics of the included studies

Ref.	Year of publication	Country	Study design	Founding sources	Patient spectrum	Inclusion criteria	Disease activity	No. of patients	Age, yr, mean (range)or mean ± SD	Gender, male: female
Del Vescovo et al[19]	2008	Italy	Prospective	NR	Known CD/healthy controls	Proven terminal ileum CD/no history of bowel disease	8 active CD, 8 non-active CD, 7 healthy controls	23	37.5 ± 17.41	15:8
Grieser et al[18]	2012	Germany	Retrospective	NR	Known CD	Referred to MRI for evaluation of disease activity	24 active CD, 24 patients non-active CD	48	37 ± 11	16:32
Koh et al[10]	2001	England	Prospective	NR	Known CD	Clinically symptoma-tic patients referred to MRI by gastroenterologists	23 active CD, 7 patients non-active CD	30	37.6 (18-58)	14:16
Quaia et al[17]	2014	Italy	Retrospective	NR	Known CD	Clinically symptoma-tic patients referred to MRI for evaluation of disease activity	47 active CD, 44 patients non-active CD	91	39.6 ± 17.1	47:44
Zappa et al[11]	2011	France	Retrospective	NR	Known CD	Patients who were to undergo bowel resection for small bowel CD	42 active CD, 11 patients non-active CD	53	35 (15-74)	28:25

¹Data are relative to patients with CD. CD: Crohn’s disease; MRI: Magnetic resonance imaging; NR: Not reported; SD: Standard deviation.