Natural history of children with mild Crohn’s disease

Table 3 Predictors of escalation to immunomodulators among mild Crohn’s patients

	Univariate	P value
	Hazard ratio (95%CI)
Age at diagnosis	1.24 (0.97-1.59)	0.09
Gender (female vs male)	0.67 (0.15-3.00)	0.60
Paris location at diagnosis
Lower 1/3 of ileum +/- base of cecum	1.29 (0.30-5.66)	0.73
Colon only	0.96 (0.19-4.99)	0.96
Ileum and colon	0.50 (0.10-2.53)	0.40
Upper GI proximal to Ligament of Treitz	1.00 (0.19-5.17)	1.00
Distal to Ligament of Treitz to proximal ileum	5.46 (0.61-49.27)	0.13
Any steroids in the first 2 yr	1.26 (0.30-5.35)	0.75
Any steroids after the first 2 yr	12.1 (1.4-102.7)	0.02
Complications	5.6 (1.3-24.9)	0.02

GI: Gastrointestinal.