Predicting gastroesophageal varices through spleen magnetic resonance elastography in pediatric liver fibrosis

doi:10.3748/wjg.v25.i3.367

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 21, 2019; 25(3): 367-377
Published online Jan 21, 2019. doi: 10.3748/wjg.v25.i3.367

Table 2 Characteristics of biliary atresia patients with and without portal hypertension

		With PHT (n = 11)	Without PHT (n = 11)	P value¹
Clinical and laboratory findings	Age (yr)	10.0 (7.0-18.0)	10.0 (4.0-15.0)	0.797
	BMI (kg/m²)	16.6 (15.1-25.6)	17.4 (14.8-29.9)	0.797
	APRI	1.17 (0.47-5.00)	0.30 (0.18-1.82)	< 0.001
Liver MRI findings	Spleen size (cm)	14.6 (10.9-19.0)	9.6 (7.1-12.1)	< 0.001
	Spleen size ratio	1.30 (0.97-1.73)	0.91 (0.63-1.06)	< 0.001
	Liver fat fraction (%)	3.0 (1.6-7.0)	2.0 (1.0-18.0)	0.300
	Liver T2* value (msec)	22.5 (15.0-38.8)	24.1 (17.5-64.1)	0.654
	Liver MRE value (kPa)	3.7 (2.9-6.0)	3.1 (2.5-5.7)	0.056
	Spleen MRE value (kPa)	11.1 (7.1-17.8)	7.6 (5.0-9.6)	< 0.001

¹From the Mann-Whitney U test. The values are the median (range). BMI: Body mass index; APRI: Aspartate aminotransferase to platelet ratio index; MRE: Magnetic resonance elastography; MRI: Magnetic resonance imaging; PHT: Portal hypertension.

Citation: Yoon H, Shin HJ, Kim MJ, Han SJ, Koh H, Kim S, Lee MJ. Predicting gastroesophageal varices through spleen magnetic resonance elastography in pediatric liver fibrosis. World J Gastroenterol 2019; 25(3): 367-377
URL: https://www.wjgnet.com/1007-9327/full/v25/i3/367.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i3.367