Copyright
©The Author(s) 2019.
World J Gastroenterol. Aug 7, 2019; 25(29): 3972-3984
Published online Aug 7, 2019. doi: 10.3748/wjg.v25.i29.3972
Published online Aug 7, 2019. doi: 10.3748/wjg.v25.i29.3972
Tissue samples, n = 42 | Serum samples | ||
Colorectal cancer, n = 126 | Healthy controls, n = 48 | ||
Age | |||
mean ± SD | 56.8 ± 6.5 | 56.9 ± 5.9 | 56.3 ± 6.4 |
Median (range) | 57 (44-73) | 58 (38-74) | 58 (38-73) |
Gender | |||
Male | 27 | 85 | 33 |
Female | 15 | 41 | 15 |
Tumor site | |||
Colon | 17 | 58 | |
Rectum | 25 | 68 | |
Tumor size in cm | |||
≥ 5 | 12 | 43 | |
< 5 | 30 | 83 | |
pT, TNM | |||
T1+T2 | 33 | 93 | |
T3+T4 | 9 | 33 | |
Lymph node metastasis | |||
Positive | 18 | 71 | |
Negative | 22 | 55 | |
Clinical stage, TNM | |||
III | 13 | 72 | |
I+II | 29 | 54 | |
Pathological differentiation | 26 | 59 | |
Well/moderate Poor | 16 | 67 | |
high vs low | |||
Lymph node metastasis, positive vs negative | 0.988 | ||
0.225 | |||
Clinical stage of | 0.440 | ||
TNM, III vs I + II | 2.789 | ||
Pathological differentiation, well/moderate vs poor | |||
Serum lncRNA | |||
MEG3 expression, |
- Citation: Wang W, Xie Y, Chen F, Liu X, Zhong LL, Wang HQ, Li QC. LncRNA MEG3 acts a biomarker and regulates cell functions by targeting ADAR1 in colorectal cancer. World J Gastroenterol 2019; 25(29): 3972-3984
- URL: https://www.wjgnet.com/1007-9327/full/v25/i29/3972.htm
- DOI: https://dx.doi.org/10.3748/wjg.v25.i29.3972