MiR-205 mediated APC regulation contributes to pancreatic cancer cell proliferation

doi:10.3748/wjg.v25.i28.3775

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 28, 2019; 25(28): 3775-3786
Published online Jul 28, 2019. doi: 10.3748/wjg.v25.i28.3775

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Figure 2 Detection of expression of miR-205 in pancreatic cancer tissues and cell lines by qRT-PCR. A: MiR-205 was up-regulated in pancreatic cancer tissues (n = 41); B: MiR-205 was up-regulated in pancreatic cancer cell lines (PANC-1, BXPC-3, and SW1990) compared with normal human pancreatic duct epithelial cell line HPDE6 (P < 0.05); C: MTT assay. Cell viability was significantly increased in cells with overexpression of miR-205 compared with control cells in a time-dependent manner; D: Colony formation assay. The effect of miR-205 overexpression on cell proliferation was evaluated.

Citation: Qin RF, Zhang J, Huo HR, Yuan ZJ, Xue JD. MiR-205 mediated APC regulation contributes to pancreatic cancer cell proliferation. World J Gastroenterol 2019; 25(28): 3775-3786
URL: https://www.wjgnet.com/1007-9327/full/v25/i28/3775.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i28.3775