Comparison of the use of wireless capsule endoscopy with magnetic resonance enterography in children with inflammatory bowel disease

Table 3 Magnetic resonance imaging and wireless capsule endoscopy positivity predictive of small bowel involvement in reference pediatric Crohn’s disease activity index > 10 and to histology

	Reference standard is PCDAI > 10 indicate active CD				Reference standard is histology in ileum and duodenum
	CD only patients (n = 20)				Histology available samples only (n = 14)
	MRE		WCE		MRE		WCE
	Value	95%CI	Value	95%CI	Value	95%CI	Value	95%CI
SEN	100%	54.07% to 100%	83.3%	35.88% to 99.58%	62.50%	24.49% to 91.48%	50.00%	15.70% to 84.30%
SP	57.14%	28.86% to 82.34%	78.6%	49.20% to 95.34%	50.00 %	11.81% to 88.19%	83.33 %	35.88% to 99.58%
PPV	50%	35.32% to 64.68%	62.5%	36.49% to 82.86%	62.50%	38.87% to 81.37%	80.00%	36.99% to 96.46%
NNP	100%		91.7%	64.29% to 98.53%	50.00 %	23.14% to 76.86%	55.56 %	36.43% to 73.17%
Accuracy	70%	45.72 to 88.11%	80.0%	56.34% to 94.27%	57.14%	28.86-82.34%	64.29%	35.14% to 87.24%

SEN: Sensitivity; SP: Specificity; PPN: Positive predictive value; NNP: Negative predictive value; MRE: Magnetic resonance enterography; PCDAI: Pediatric Crohn’s Disease Activity Index; WCE: Wireless capsule endoscopy; CD: Crohn’s disease.