Raddeanin A promotes apoptosis and ameliorates 5-fluorouracil resistance in cholangiocarcinoma cells

Figure 6 Effects of raddeanin A on cell cycle- and apoptosis-related protein expression in RBE cell line treated with 13 μg/mL raddeanin A for 48 h. A and B: Apoptosis-related protein expression detected by Western blot; C and D: Cell cycle-related protein expression detected by Western blot. Data are expressed as the mean ± standard deviation. Unique letters shared by the bars suggest significant differences between groups and P < 0.05 was regarded to be statistically significant. RA: Raddeanin A; 5-Fu: 5-fluorouracil; COX-2: Cyclooxygenase-2.