Screening of aptamers and their potential application in targeted diagnosis and therapy of liver cancer

Table 1 Current literature summary of aptamers for in vitro detection of liver cancer

First author	Year	Aptamer	Target	System for detection	Method for detection
Hu et al[51]	2017	TLS11a	HepG2 cells	Bio-TLS11a and SA-FSNPs	Fluorescence Microscopy
Wang et al[52]	2016	sLex-AP	CTCs	CTC-BioT Chip	Fluorescence Microscopy
Joo et al[53]	2017	AFB1-Apt	AFB1	FAM modified AFB1-Apt and GO	Fluorescence Microscopy
Kaur et al[54]	2019	SL2-B	HepG2 cells	QDs labeled SL2-B	Fluorescence Microscopy
Zhou et al[55]	2019	Slow-off aptamer (TD10); fast-off aptamer	DKK1 protein	5′ amino C6 modified TD10-based ELISA; 5′ FAM labeled fast-off aptamer	ELISA (TD10); dot blot and flow cytometry (fast-off aptamer)