Opinion Review
Copyright ©The Author(s) 2019.
World J Gastroenterol. Jul 7, 2019; 25(25): 3116-3122
Published online Jul 7, 2019. doi: 10.3748/wjg.v25.i25.3116
Table 1 Mouse injury models used for plasticity studies
StudyPlastic cell identifiedInjury model used
Tian et al[18]Bmi1+ cellDTR Lgr5+ ablation
Roth et al[19]Paneth cell12Gy radiation
van Es et al[16]Dll1+ cell6Gy radiation
Buczacki et al[17]Label-retaining cell6Gy radiation, doxorubicin or hydroxyurea
Asfaha et al[20]Upper crypt progenitor12Gy radiation +/- 5-Fluorouracil
Tetteh et al[27]Alpi1+ enterocyteDTR Lgr5+ ablation
Jadhav et al[9]Goblet cell progenitorsDTR Lgr5+ ablation
Yan et al[21]Enteroendocrine cell12Gy radiation
Ishibashi et al[22]Atoh1+ cellDSS (1.75%) for 5 d
Nusse et al[23]Lgr5- crypt cellParasite infection
Schmitt et al[24]Paneth cellDSS (3%) for 1 wk
Tomic et al[26]Atoh1+ cell6Gy radiation, AOM or 2% DSS
Yu et al[25]Lyz1+ Paneth cell12Gy radiation
Castillo et al[28]Atoh1+ cellDSS (2.5%-3%) for 5 d