Imaging biomarkers for the treatment of esophageal cancer

Table 2 Summary of reports on diffusion-weighted imaging in esophageal cancer

	Year	Patients	Biomarker candidate	Prediction of treatment outcome
Aoyagi et al[33]	2011	80	Baseline ADC	High baseline ADC associated with favorable survival after CRT
Imanishi et al[36]	2013	27	Early change of ADC, post-CRT ADC	Increase of ADC/high post-CRT ADC associated with good response to CRT
De Cobelli et al[35]	2013	32	Baseline ADC	High baseline ADC associated with poor response to CRT
Van Rossum et al[39]	2015	20	Early change of ADC	Increase of ADC associated with good response to CRT
Wang et al[37]	2016	38	Early change of ADC, post-CRT ADC	Increase of ADC/high post-CRT ADC associated with good response to CRT
Li et al[38]	2017	28	Early change of ADC, post-CRT ADC	Increase of ADC/high post-CRT ADC associated with good response to CRT
Cong et al[34]	2019	52	Baseline ADC	High baseline ADC associated with good response to RT

ADC: Apparent diffusion coefficient; CRT: Chemoradiation therapy; RT: Radiation therapy.