Long-lasting discussion: Adverse effects of intraoperative blood loss and allogeneic transfusion on prognosis of patients with gastric cancer

Table 2 Studies of effects of blood transfusion on prognosis in patients with gastric cancer

Study	Period	Sample size	Selected group	Rates of received BTF	Timing of transfusions	Adverse effect of BTF on prognosis
Kaneda et al[44], 1987	1976-1980	231	Not specified	51%	Not specified	Yes (Survival)
Ojima et al[19], 2009	1991-2002	856	Curative gastrectomy	18%	Pre + Intra + Post	Yes (Survival)
Squires et al[20], 2015	2000-2012	765	Curative gastrectomy	22%	Intra + Post	Yes (Survival, Recurrence)
Kanda et al[6], 2016	1999-2014	250	stage II /III	23%	Pre + Intra + Post	Yes (Survival, Recurrence)
Kampschoer et al[45], 1989	1976-1981	1000	Curative gastrectomy	37%	Pre + Intra + Post	No (Survival)
Kamei et al[14], 2009	1992-2003	146	Curative gastrectomy	13%	Not specified	No (Peritoneal recurrence)
Pacelli et al[46], 2011	1990-2005	927	Curative gastrectomy	35%	Pre + Intra + Post	No (Survival)
Liang et al[8], 2013	2003-2007	845	stage I-III	25%	Pre + Intra + Post	No (Survival)
Rausei et al[47], 2013	1995-2011	224	stage I-III	20%	Pre + Intra + Post	No (Survival)

BTF: Blood transfusion; Pre: Preoperative; Intra: Intraoperative; Post: Postoperative.