Gadoxetic acid-enhanced magnetic resonance imaging can predict the pathologic stage of solitary hepatocellular carcinoma

Table 3 The odds ratios for imaging features favoring a diagnosis of pathologic stage T2 over pT1

Features	Crude OR	95%CI	P value
T2 hyperintensity	1.904	(0.376-9.639)	0.436
T1 hypointensity	0.761	(0.201-2.874)	0.687
Arterial enhancement	2.714	(0.306-24.085)	0.370
Corona enhancement	2.671	(1.101-6.480)	0.030
Washout appearance	1.043	(0.246-4.419)	0.954
Capsular appearance	0.545	(0.246-1.208)	0.135
Hypointensity of tumor in the HB phase	0.250	(0.022-2.847)	0.264
Peritumoral hypointensity in HB phase	2.203	(0.961-5.049)	0.062
Hypointense-rim in the HB phase	0.378	(0.130-1.098)	0.074
Intratumoral fat	0.817	(0.319-2.093)	0.674
Mosaic architecture	1.266	(0.553-2.895)	0.577
Hyperintensity on DWI	N/A	N/A	N/A
Hypointensity ADC map	0.935	(0.426-2.050)	0.866
Tumor margin
Smooth (baseline)
Non-smooth	1.407	(0.594-3.333)	0.437
AJCC v.8
cT1a (baseline)	1.00	Reference
cT1b	6.727	(1.483-30.517)	0.014

Because all patients in the study group demonstrated hyperintensity on diffusion weighted imaging, we were not able to calculate the odds ratio and P value. HB: Hepatobiliary; DWI: Diffusion weighted imaging; ADC: Apparent diffusion coefficient; AJCC: American Joint Committee on Cancer; pT1: Pathologic stage T1; pT2: Pathologic stage T2; OR: Odds ratio; CI: Confidence interval.