Interleukin-22 receptor 1 is expressed in multinucleated giant cells: A study on intestinal tuberculosis and Crohn's disease

doi:10.3748/wjg.v25.i20.2473

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 28, 2019; 25(20): 2473-2488
Published online May 28, 2019. doi: 10.3748/wjg.v25.i20.2473

Table 8 Genetic model analysis of rs2227473 in the intestinal tuberculosis population

Genetic model	Genotype	HCs (n)	ITB (n)	OR (95%CI)	P-value	OR (95%CI)¹	P-value¹
Dominant	GG	373	112	1.00		1.00
	GA + AA	127	21	0.58 (0.35-0.96)	0.034	0.58 (0.34-0.98)	0.040
Recessive	GA + GG	483	131	1.00		1.00
	AA	17	2	0.43 (0.10-1.90)	0.268	0.45 (0.10-1.99)	0.291
Co-dominant	GG	373	112	1.00		1.00
	AA	17	2	0.40 (0.09-1.74)	0.219	0.50 (0.11-2.33)	0.379
	GG	373	112	1.00		1.00
	GA	110	19	0.61 (0.36-1.03)	0.064	0.63 (0.37-1.08)	0.091

HCs: Healthy controls; ITB: Intestinal tuberculosis; OR: Odds ratio; CI: Confidence interval.

¹Adjusted for gender, age, smoking and drinking history.

Bold indicates the statistical significance (P < 0.05).

Citation: Yu ZQ, Wang WF, Dai YC, Chen XC, Chen JY. Interleukin-22 receptor 1 is expressed in multinucleated giant cells: A study on intestinal tuberculosis and Crohn's disease. World J Gastroenterol 2019; 25(20): 2473-2488
URL: https://www.wjgnet.com/1007-9327/full/v25/i20/2473.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i20.2473