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Copyright ©The Author(s) 2019.
World J Gastroenterol. Jan 14, 2019; 25(2): 178-189
Published online Jan 14, 2019. doi: 10.3748/wjg.v25.i2.178
Table 4 Description of studies using an empirical treatment strategy to reduce upper gastrointestinal endoscopies
StudyCountrySampleStrategyUGIE avoided
Laheij et al[59], 1998Netherlands80 patients2-wk PPI treatment. HP test and treat for persistent symptoms.69%
Kjeldsen et al[60], 2007Denmark184 patientsUGIE vs 2-wk PPI treatment and HP testing + UGIE (no improvement, recurrence at age ≥ 45, or HP- and age < 45 yr), eradication (HP+ and age < 45 yr), or PPI 2 additional weeks (HP-, age < 45 yr, and reflux+)63%
Bytzet et al[62], 1994Denmark206 patients4 weeks H2RA treatment34%