Combined evaluation of biomarkers as predictor of maintained remission in Crohn’s disease

Figure 3 Positive and negative predictive values of Crohn’s disease activity index, C-reactive protein and faecal calprotectin, alone or combined, after 12 wk of anti-tumor necrosis factor to predict corticosteroids-free remission at week 52. Faecal calprotectin (Fcal) improvement (Fcal < 300 μg/g at W12; or, for patients with initial Fcal < 300 μg/g, at least 50% decrease of Fcal or normalization of Fcal (< 100 μg/g). CDAI: Crohn’s disease activity index; CRP: C-reactive protein; Fcal: Faecal calprotectin.