Meta-Analysis
Copyright ©The Author(s) 2019.
World J Gastroenterol. May 21, 2019; 25(19): 2383-2401
Published online May 21, 2019. doi: 10.3748/wjg.v25.i19.2383
Table 4 Diagnostic accuracy parameters for colorectal cancer detection based on quantitative faecal immunochemical test for haemoglobin threshold concentration and brand
BrandThreshold(µg/g faeces)Author, yearSensitivity1Specificity1
Mixed cohorts
OC-Sensor®25Rozen, 2010[17]60.0 (36.1-80.9)95.2 (94.0-96.2)
OC-Sensor®30Rozen, 2010[17]55.0 (31.5-76.9)95.8 (94.7-96.7)
OC-Sensor®40Rozen, 2010[17]55.0 (31.5-76.9)96.3 (95.3-97.2)
OC-Sensor®40van Turenhout, 2014[18]75.4 (63.5-84.9)94.8 (93.9-95.6)
OC-Sensor®60Symonds 2016[23]63.6 (50.9-75.1)91.9 (90.3-93.3)
OC-Sensor®80Symonds 2016[23]59.1 (46.3-71.0)93.4 (91.9-94.7)
HM-JACK®33Woo, 2005[19]50.0 (11.8-88.2)83.5 (73.5-90.9)
FOB Gold®10Auge, 2018[30]91.7 (71.5-98.5)82.2 (79.6-84.5)
FOB Gold®20Auge, 2018[30]87.5 (66.5-96.7)86.0 (83.6-88.1)
FOB Gold®30Auge, 2018[30]83.3 (61.8-94.5)89.2 (87.0-91.1)
FOB Gold®40Auge, 2018[30]83.3 (61.8-94.5)90.3 (88.2-92.1)
FOB Gold®50Auge, 2018[30]83.3 (61.8-94.5)91.4 (89.4-93.1)
FOB Gold®60Auge, 2018[30]83.3 (61.8-94.5)91.8 (89.9-93.5)
100% Symptomatic
HM-JACK®20Parente, 2012[24]61.7 (46.4-75.5)88.8 (84.1-92.6)
HM-JACKarc®7Widlak, 2017[28]84.0 (63.9-95.5)93.1 (90.2-95.4)