Beneficial effect of probiotics supplements in reflux esophagitis treated with esomeprazole: A randomized controlled trial

Figure 2 Efficacy of esomeprazole 20 mg b. i.d. and live combined Bacillus subtilis and Enterococcus faecium enteric-coated capsules 500 mg t.i.d. A: Reflux diagnostic questionnaire scores, B: Gastrointestinal symptom rating scale scores, C: Endoscopic healing rates in the probiotics and placebo groups after eight weeks of treatment. Probiotics refers to esomeprazole 20 mg b.i.d. and live combined Bacillus subtilis and Enterococcus faecium enteric-coated capsules 500 mg t.i.d. treatment; placebo refers to esomeprazole 20 mg b.i.d. and placebo treatment. ^aP < 0.05; ^bP < 0.01; ^cP < 0.001. RDQ: Reflux diagnostic questionnaire; GSRS: Gastrointestinal symptom rating scale.